Abdullah Mohammed Al-Majid

Jan 12, 2025 | mdpi.com | Assem Barakat |Fardous El-Senduny |Mohammad Shahidul Islam |Abdullah Mohammed Al-Majid

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Aug 10, 2023 | onlinelibrary.wiley.com | Mohammad Shahidul Islam |Abdullah Mohammed Al-Majid |Matti Haukka |Zahida Parveen

Supporting Information Filename Description cbdd14299-sup-0001-Supinfo.docxWord 2007 document , 4.6 MB Data S1: REFERENCES , , , , , , & (2020). Design, construction, and characterization of a new regioisomer and diastereomer material based on the spirooxindole scaffold incorporating a sulphone function. Symmetry, 12(8), 1337. , , , & (2019). Spiroindolone analogues as potential hypoglycemic with dual inhibitory activity on α-amylase and α-glucosidase.

May 30, 2023 | onlinelibrary.wiley.com | Mohammad Shahidul Islam |Abdullah Mohammed Al-Majid |Mohamed S. Nafie |Refaah Mousa Al-Jassas

A series of 16 novel spirooxindole analogs 8a–p were designed and constructed via cost-effective single-step multicomponent [3+2] cycloaddition reaction of azomethine ylide (AY) generated in situ from substituted isatin (6a–d) with suitable amino acids (7a–c) and ethylene-engrafted pyrazole derivatives (5a,b). The potency of all compounds was assayed against a human breast cancer cell line (MCF-7) and a human liver cell line (HepG2).