Achim Kramer

Nov 27, 2024 | genesdev.cshlp.org | Achim Kramer

2 1Center of Brain, Behavior, and Metabolism, Institute of Neurobiology, University of Lübeck, 23562 Lübeck, Germany; 2Charité–Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt Universität zu Berlin, Laboratory of Chronobiology, Berlin Institute of Health, 10117 Berlin, Germany Corresponding author: achim.kramer{at}charite.de Footnotes Article published online ahead of print.

Aug 21, 2024 | nature.com | Jeff Didier |Sébastien De Landtsheer |Anna-Marie Finger |Johannes H. Schulte |Thomas C Sauter |Achim Kramer

AbstractThe circadian clock, a fundamental biological regulator, governs essential cellular processes in health and disease. Circadian-based therapeutic strategies are increasingly gaining recognition as promising avenues. Aligning drug administration with the circadian rhythm can enhance treatment efficacy and minimize side effects. Yet, uncovering the optimal treatment timings remains challenging, limiting their widespread adoption.

May 22, 2023 | pubmed.ncbi.nlm.nih.gov | Achim Kramer

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May 22, 2023 | onlinelibrary.wiley.com | Achim Kramer |Humboldt-Universität zu Berlin

Circadian medicine developed from chronobiology, which deals with temporal processes in biological systems. Humans have an internal circadian clock that it is genetically determined, synchronized with the environment by light and food, and controls myriad time-of-day-dependent physiological processes in each cell of our body.1, 2 In 2017, Rosbash, Hall and Young received the Nobel Prize in Physiology or Medicine for elucidating the molecular mechanism of the circadian clock.