Aditi Bhargava

Feb 28, 2024 | biorxiv.org | Aditi Bhargava |Johannes Knapp |Oliver Fiehn

AbstractPosttraumatic stress disorder (PTSD) is widely recognized as a common consequence of trauma exposure. Women are at particularly high risk, with some studies finding that women develop PTSD at twice the rate of men, despite greater trauma exposure in men. Lipids and their metabolites (lipidome) regulate a myriad of key biological processes and pathways such as membrane integrity, oxidative stress, and neuroinflammation in the brain by maintaining neuronal connectivity and homeostasis.