Adrien Rizzi

May 3, 2023 | nature.com | Vincent Charron-Lamoureux |Adrien Rizzi |Philippe Dauphin-Ducharme |Claude Y. Legault |Jean-Philippe Bellenger

AbstractSiderophores are soluble or membrane-embedded molecules that bind the oxidized form of iron, Fe(III), and play roles in iron acquisition by microorganisms. Fe(III)-bound siderophores bind to specific receptors that allow microbes to acquire iron. However, certain soil microbes release a compound (pulcherriminic acid, PA) that, upon binding to Fe(III), forms a precipitate (pulcherrimin) that apparently functions by reducing iron availability rather than contributing to iron acquisition.