Agnieszka N. Urbanek

Jan 13, 2025 | advanced.onlinelibrary.wiley.com | Agnieszka N. Urbanek |Emma Garland |Emily Prescott |Marianne King

1 Introduction Protein complexes are basic components of cells, executing essential biochemical processes and orchestrating the smooth functioning of life at the molecular level. The function of these aggregates hinges on the precise and regulated interactions among their molecular components. When the delicate balance of these interactions is disrupted, aberrant protein assemblies can form.

Nov 12, 2024 | biorxiv.org | Agnieszka N. Urbanek |Emma Garland |Emily Prescott |Marianne King

AbstractDetermining the structure-function relationships of protein aggregates is a fundamental challenge in biology. These aggregates, whether formed in vitro, within cells, or in living organisms, present significant heterogeneity in their molecular features such as size, structure, and composition, making it difficult to determine how their structure influences their functions.