Ahmed Moustafa

Aug 11, 2024 | nature.com | Ian R. Monk |Ying-Tsun Cheng |Camilla Predella |Jack Boylan |Ahmed Moustafa |Gaurav Kumar Lohia | +5 more

AbstractStaphylococcus aureus is a pulmonary pathogen associated with substantial human morbidity and mortality. As vaccines targeting virulence determinants have failed to be protective in humans, other factors are likely involved in pathogenesis. Here we analysed transcriptomic responses of human clinical isolates of S. aureus from initial and chronic infections. We observed upregulated collagenase and proline transporter gene expression in chronic infection isolates.

Sep 25, 2023 | softpedia.com | Ahmed Moustafa

JAligner is a versatile tool primarily used for sequence alignment, a fundamental task in bioinformatics and computational biology. The idea behind the tool is to provide a flexible and memory-efficient solution for comparing biological sequences, aiding researchers and scientists in various fields, such as genomics, proteomics, and evolutionary biology, to make sense of complex sequence data.