Aik Seng Ng

3 weeks ago | nature.com | Eoghan J. Mulholland |Hayley L. Belnoue-Davis |Aik Seng Ng |Kim S. Midwood |Neesha Dedi |Rachel A. Ridgway | +6 more

AbstractIn homeostasis, counterbalanced morphogen signalling gradients along the vertical axis of the intestinal mucosa regulate the fate and function of epithelial and stromal cell compartments. Here, we use a disease-positioned mouse and human tissue to explore the consequences of pathological BMP signalling dysregulation on epithelial-mesenchymal interaction.