Alastair K Denniston

Oct 29, 2024 | nature.com | Olalekan Lee Aiyegbusi |Alastair K Denniston |Rosie Harding |Sarah Hughes |Dipak Kotecha |Harlan M. Krumholz | +3 more

AbstractDecentralized clinical trials involving the use of digital tools to facilitate remote research are gaining momentum. Rapid advancements in digital technologies have supported the adoption of these trials. These innovations facilitate virtual interactions between clinical trial teams and participants by making it easier to collect, transfer and store electronic data.

Jul 29, 2024 | nature.com | Benjamin Ng |Victoria Ngai |Gary Collins |David Moher |Melissa McCradden |Melanie Calvert | +4 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-45355-3, published online 22 February 2024The original version of this Article omitted from the author list the 2nd and 3rd authors, Carrie D. Llewellyn and Richard O. de Visser, respectively. Carrie D. Llewellyn and Richard O. de Visser are from the Department of Primary Care and Public Health, Brighton and Sussex Medical School, UK.

Jul 11, 2024 | researchprotocols.org | Alastair K Denniston

BackgroundPurposeReporting of Protocol and Systematic ReviewSystematic Review RegistrationInformation SourcesSearch StrategyMAUDE (provided by the FDA)This database will be searched using the openFDA application programming interface (API). The openFDA was set up by the first Chief Health Information Officer in March 2013 and enables public access to relevant data including drug and medical device AEs.The API can be searched to request several data points.

Jun 28, 2024 | researchprotocols.org | Alastair K Denniston

BackgroundAI Errors and Patient Harms“An unfavourable outcome that occurs during or after the use of a drug or other intervention but is not necessarily caused by it” [,]“Any outputs of the AI system which are inaccurate, including those which are inconsistent with expected performance and those which can result in harm if undetected or detected too late.” []“The tendency to malfunction in the presence of certain conditions.

Feb 22, 2024 | nature.com | Benjamin Ng |Victoria Ngai |Gary Collins |David Moher |Melissa McCradden |Melanie Calvert | +4 more

AbstractThe Consolidated Standards of Reporting Trials extension for Artificial Intelligence interventions (CONSORT-AI) was published in September 2020. Since its publication, several randomised controlled trials (RCTs) of AI interventions have been published but their completeness and transparency of reporting is unknown.