Harlan M. Krumholz

Editor-in-Chief at JACC Specialty Journals

Harold H. Hines Jr Professor, Yale Univ; Director, YNHH CORE; Editor-in-Chief, JACC. Working to improve the future for those who follow us...

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Articles

Medicine’s Responsibility in Divided Times: Moving Mountains Together

1 month ago | jacc.org | Harlan M. Krumholz

IntroductionWorld history has its cycles. Now, we are experiencing rising tensions among and within countries. Geopolitical issues dominate the news. For some, international travel is becoming fraught. Economic policies are trending toward isolationism, and globalism appears on the decline. Moreover, the pace of change is accelerating.
Opinion | How to Lead a Chronic Disease Revolution

1 month ago | wsj.com | Akiko Iwasaki |Harlan M. Krumholz

Washington has an opportunity to help tens of millions. Millions of Americans struggle with debilitating fatigue, cognitive difficulties and heart palpitations—symptoms of what is called long Covid. The sheer number of people suffering has brought unprecedented public attention to the wider issue of postinfection illnesses, providing a revolutionary opportunity that Washington should seize. Postinfection syndromes aren’t unique to Covid.
Advancing Care in Cardiogenic Shock: Evidence, Innovation, and Commitment

2 months ago | jacc.org | Harlan M. Krumholz

IntroductionCardiogenic shock remains one of the most formidable challenges in cardiovascular medicine, marked by persistently high morbidity and mortality rates despite significant advances in treatment. In recognition of the urgent need for deeper insights and novel therapeutic strategies, JACC is committed to advancing the field through rigorous science, critical evaluations, and expert perspectives.
Featuring Content From Across the JACC Journals:

2 months ago | jacc.org | Harlan M. Krumholz

IntroductionYou may have noticed an important change at JACC. We have started to include content from the JACC Journals in some of our issues. This initiative promotes outstanding content from across the entire JACC portfolio. JACC JournalsJACC is proud to be more than a single journal—we are a dynamic family of 10 exceptional journals, each dedicated to a unique and vital area within cardiovascular medicine.
Articulating the JACC Journals’ Direction in Times of Global Change:

2 months ago | jacc.org | Harlan M. Krumholz |Biykem Bozkurt |Y. Chandrashekhar |Bonnie Ky

IntroductionIn an era marked by societal divisions, evolving views on expertise, and rapid technological advancements in health care, the JACC journals stand as a steadfast leader of evidence-based knowledge. These broader transformations are occurring alongside rapid technological advancement in health care delivery, changing demographic patterns, and growing gaps in health care equity across populations.
Preprints: A Revolution in Cardiovascular Science

Feb 18, 2025 | jacc.org | Harlan M. Krumholz |Joshua D. Wallach

IntroductionScientific publishing is transforming, and preprints are leading the charge. Preprints enhance the rapid communication of discoveries and insights by allowing researchers to share completed work before peer review. This approach complements peer review, which retains its importance, fostering collaboration and accelerating scientific progress.
Articulating the JACC Journals' Direction in Times of Global Change:

Feb 12, 2025 | jacc.org | Harlan M. Krumholz |Biykem Bozkurt |Y. Chandrashekhar |Bonnie Ky

JACC Journals › JACC › Archives › Just Accepted JACC. . Epublished DOI: 10.1016/j.jacc.2025.02.006FiguresReferencesRelatedDetails InformationCopyright © 2025, American College of Cardiology Foundation. Published by Elsevier Article History ReceivedFebruary 3, 2025AcceptedFebruary 3, 2025Published onlineFebruary 12, 2025
The NIH’s drastic cut to indirect cost rates is a critical threat to U.S. research infrastructure

Feb 8, 2025 | statnews.com | Harlan M. Krumholz

The National Institutes of Health has made a landmark decision that could irreparably damage the backbone of American scientific innovation: a dramatic reduction in the indirect cost rate for research grants. This sweeping policy change sets the indirect rate to 15%, a stark contrast with the 60% or more that many institutions currently rely on for essential administrative and operational costs.
Advancing Prevention: Insights From JACC's Focus Issue

Dec 2, 2024 | jacc.org | Harlan M. Krumholz

IntroductionEach year, cardiovascular disease claims millions of lives worldwide—deaths that are largely preventable. As we present this issue of JACC focused on prevention, we confront unprecedented opportunities and challenges in cardiovascular medicine. The breadth of research in this issue illustrates the dynamic evolution of cardiovascular prevention, from novel therapeutic approaches to troubling implementation gaps.
Information Disclosure, Medical Device Regulation, and Device Safety: The Case of Cook Celect IVC Filters

Nov 19, 2024 | acpjournals.org | Kushal Kadakia |Harlan M. Krumholz

Get full access to this articleView all available purchase options and get full access to this article. Supplemental MaterialReferences1. Zuckerman D, Brown P, Das A. Lack of publicly available scientific evidence on the safety and effectiveness of implanted medical devices. JAMA Intern Med. 2014;174:1781-1787. [PMID: 25265047] doi: 10.1001/jamainternmed.2014.41932. Egilman AC, Kesselheim AS, Krumholz HM, et al. Confidentiality orders and public interest in drug and medical device litigation.