Alba de Juan

Oct 15, 2024 | science.org | Alba de Juan |Leslie K. Ferrarelli |Alice Coillard |Darawan Tabtim-On

Editor’s summaryThe aryl hydrocarbon receptor (AhR), a transcription factor activated by various metabolites and xenobiotics, influences how immune cells respond to the cytokines that direct their differentiation and function. de Juan et al. found that activation of the AhR was required for the induction of a subset of transcripts by the cytokine interleukin-4 (IL-4) in human and mouse monocytes.

Oct 15, 2024 | science.org | Alba de Juan |Leslie K. Ferrarelli

AbstractToo much or too little tau in glial cells enables the accumulation of neurotoxic oxidative stress. SIGN UP FOR THE SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Tau gets a bad rap. Its aggregation in the brain causes the neurofibrillary tangles that underlie cognitive decline and brain atrophy in various neurodegenerative diseases.