Alice Coillard

Oct 15, 2024 | science.org | Alba de Juan |Leslie K. Ferrarelli |Alice Coillard |Darawan Tabtim-On

Editor’s summaryThe aryl hydrocarbon receptor (AhR), a transcription factor activated by various metabolites and xenobiotics, influences how immune cells respond to the cytokines that direct their differentiation and function. de Juan et al. found that activation of the AhR was required for the induction of a subset of transcripts by the cytokine interleukin-4 (IL-4) in human and mouse monocytes.