Alessandro Boscarelli

Nov 24, 2023 | frontiersin.org | Hubei Univeristy |Rakesh Kapoor |Alessandro Boscarelli |Nicholas Pavlidis

IntroductionThe incidence of multiple primary cancers (MPC) has shown an upward trend in the general population (1), accounting for approximately 1-16% of all cancer cases (2, 3). The etiology of MPC was found to be multifactorial, involving factors, such as genetic predisposition, environmental exposures, and lifestyle choices. The presence of MPC complicates the diagnostic process, treatment plan formulation, and prognosis assessment, and no unified standard was established.