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1 week ago | 
beckershospitalreview.com | Alexandra Murphy |Paige Twenter |Erica Carbajal
Eli Lilly completed a phase 3 trial for its weight loss drug, orforglipron, which showed promising results in evaluating its safety and efficacy for adults with Type 2 diabetes and inadequate glycemic control. The once-daily oral GLP-1 receptor agonist significantly reduced blood sugar and body weight in adults with Type 2 diabetes and had a safety profile consistent with injectable therapies, according to an April 17 news release from the drugmaker.
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1 week ago | 
beckershospitalreview.com | Mariah (Handy) Taylor |Mackenzie Bean |Erica Carbajal |Alexandra Murphy
A recent study found that up to 90% of sepsis patients may be overtreated. The study, published April 15 in Clinical Infectious Diseases and led by researchers from Brigham’s Women’s Hospital and Harvard Medical School, both in Boston, analyzed medical records of 600 randomly selected adults that were treated for suspected sepsis in seven emergency departments between 2019 and 2022. Here are four findings:1.
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1 week ago | 
beckershospitalreview.com | Mackenzie Bean |Mariah (Handy) Taylor |Erica Carbajal |Alexandra Murphy
The CDC’s Advisory Committee on Immunization Practices voted April 16 to expand use of respiratory syncytial virus vaccines among high-risk adults. The updated recommendation calls for a single vaccine dose for adults ages 50-59 with underlying medical conditions who are at increased risk for severe RSV illness. The CDC’s existing RSV vaccine guidance applies to adults ages 75 and older, as well as high-risk individuals ages 60 to 74.
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1 week ago | 
beckershospitalreview.com | Erica Carbajal |Alexandra Murphy |Paige Twenter |Kelly Gooch
The effects of the Trump administration’s decision to freeze more than $2.2 billion in federal funding to Cambridge, Mass.-based Harvard University are coming into sharper focus, as researchers begin to receive stop work orders for multimillion-dollar projects. On April 14, federal officials said they would freeze $2.2 billion in multiyear grants along with a $60 million contract to the school as part of an investigation into the university’s handling of antisemetic harassment on its campus.
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1 week ago | 
beckershospitalreview.com | Alexandra Murphy |Paige Twenter |Kelly Gooch |Kristin Kuchno
The FDA has cleared the first clinical trial to test genetically engineered pig livers in patients who have acute-on-chronic liver failure. The trial will evaluate the use of a Egenesis porcine liver genetically modified to be more compatible with the human immune system in combination with the OrganOx extracorporeal liver cross-circulation system, according to an April 15 Egenesis news release.
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1 week ago | 
beckershospitalreview.com | Paige Twenter |Alexandra Murphy |Kelly Gooch |Kristin Kuchno
Mark Cuban’s latest move to disrupt the pharmaceutical supply chain is expanding — this time, tackling the injectable drug market through a new partnership with distributor Morris & Dickson. His company, Mark Cuban Cost Plus Drug Co., is partnering with Morris & Dickson, a full-line and specialty pharmaceutical distributor, to improve access to injectables nationwide.
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1 week ago | 
beckershospitalreview.com | Alexandra Murphy |Alan Condon |Kristin Kuchno |Kelly Gooch
From capacity constraints to reimbursement pressures, health system CEOs are navigating a changing healthcare landscape. One of the top concerns in 2025 is the potential for Medicaid funding cuts. A recent report estimates hospitals could face a $31.9 billion loss in revenue if federal proposals to scale back Medicaid expansion move forward.
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1 week ago | 
beckershospitalreview.com | Alexandra Murphy |Elizabeth Gregerson
President Donald Trump has threatened tariffs on pharmaceutical imports, with U.S. Commerce Secretary Howard Lutnick confirming that the tariffs will be implemented “in a month or two,” ABC Newsreported April 13. “All those products are going to come under semiconductors, and they’re going to have a special focus type of tariff to make sure that those products get reshored.
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1 week ago | 
beckershospitalreview.com | Alexandra Murphy |Paige Twenter |Mackenzie Bean
President Donald Trump signed an executive order aimed at lowering drug prices and expanding access to affordable medications, according to an April 15 White House Fact Sheet. Through the efforts laid out in the order, the Trump administration said it aims to surpass the 22% in savings that the Biden administration achieved during the first year of the Medicare Drug Pricing Negotiation Program. Here are five things to know:The order directs HHS secretary Robert F.
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1 week ago | 
beckershospitalreview.com | Naomi Diaz |Giles Bruce |Alexandra Murphy
The Department of Health and Human Services could face a critical breakdown in its IT and cybersecurity systems after a sweeping reduction in force that eliminated key staff and leadership, Wired reported April 14, citing four current and former agency employees. More than 150 workers in HHS’ Office of the Chief Information Officer were among hundreds of administrative staff laid off April 1, according to the report.
