Alison Rose Ohringer

Oct 28, 2024 | jamanetwork.com | Alison Rose Ohringer |Chan Zuckerberg Biohub

Guideline-Directed Medical Therapy Intolerance in Heart Failure An 89-year-old woman with severe peripheral arterial disease and chronic left lower extremity limb ischemia, heart failure with reduced ejection fraction (HFrEF) of 35% to 40%, and paroxysmal atrial flutter presented to the emergency department for lethargy, weakness, and left foot pain for 1 week. Eighteen months prior, the patient was diagnosed with HFrEF.