Allison Williams

Dec 5, 2023 | nature.com | Alejandro Tejada-Arranz |Thibaut Douché |Mariette Matondo |Allison Williams |Bertrand Raynal |Ben F. Luisi | +2 more

AbstractIn the gastric pathogen Helicobacter pylori, post-transcriptional regulation relies strongly on the activity of the essential ribonuclease RNase J. Here, we elucidated the crystal and cryo-EM structures of RNase J and determined that it assembles into dimers and tetramers in vitro. We found that RNase J extracted from H. pylori is acetylated on multiple lysine residues. Alanine substitution of several of these residues impacts on H. pylori morphology, and thus on RNase J function in vivo.

Sep 14, 2023 | pdxmonthly.com | Allison Williams

ONCE A TRAVELER is old enough to sign for a rental car, their outlook on hostels turns into a veritable Lethal Weapon quote about “getting too old for this shit.” Inexplicably linked to the kind of European vacation starring a tattered backpack and bad weed, the hostel is usually about low prices. But it’s also about even lower barriers to socialization, and spending a vacation beyond the tourist bus.