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Sep 9, 2024 | 
link.aps.org | Uroš Barać |Kyung Hee |Marko Gosak |Alma Mater Europaea
When individual oscillators age and become inactive, the collective dynamics of coupled oscillators is often affected as well. Depending on the fraction of inactive oscillators or cascading failures that percolate from crucial information exchange points, the critical shift toward macroscopic inactivity in coupled oscillator networks is known as the aging transition.
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Aug 26, 2024 | 
academic.oup.com | Alma Mater Europaea |Peter J. H
Gait impairments, balance issues, and falls stand as significant hallmarks of Parkinson's disease (PD), markedly reducing quality of life, escalating healthcare expenses, and amplifying the burden on caregivers.1,2 As the condition progresses, debilitating postural instability and gait difficulties become increasingly prevalent.3 These motor impairments pose considerable therapeutic challenges, typically showing increasing refractoriness to dopaminergic treatments.4-6 This indicates that...
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Dec 5, 2023 | 
link.aps.org | Andre S. Sunahara |Departamento de Física |Alma Mater Europaea |Kyung Hee
Abstract A common expectation is that career productivity peaks rather early and then gradually declines with seniority. But whether this holds true is still an open question. Here we investigate the productivity trajectories of almost 8500 scientists from over 50 disciplines using methods from time-series analysis, dimensionality reduction, and network science, showing that there exist six universal productivity patterns in research.
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Nov 22, 2023 | 
link.aps.org | Alma Mater Europaea |Uroš Barać |Marko Gosak
Pancreatic beta cells are coupled excitable oscillators that synchronize their activity via different communication pathways. Their oscillatory activity manifests itself on multiple timescales and consists of bursting electrical activity, subsequent oscillations in the intracellular Ca2+, as well as oscillations in metabolism and exocytosis.
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Jul 11, 2023 | 
frontiersin.org | Izmir Katip Celebi |Alanya Alaaddin Keykubat |Alma Mater Europaea |Yilmaz Kemal
1. Introduction
Brain–computer Interfaces (BCIs) help to establish and realize the interaction between humans and computers using physiological signals acquired from the brain (Tiwari et al., 2022). It allows individuals who can not control a part of their resulting from paralysis or similar diseases but who are conscious to communicate with the outside world and control the robot arm, wheelchair, computer, and similar devices with thought power.
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Jul 6, 2023 | 
frontiersin.org | Alma Mater Europaea |Kyung Hee |Hamid Reza Baradaran |Drazenka Pongrac Barlovic
1. IntroductionType 2 diabetes mellitus (T2DM) is a chronic disease affecting millions of people worldwide and its prevalence is increasing at an alarming rate (1). Scientific research into the profiling of individuals with diabetes aims to identify the factors that contribute to the development and progression of the disease and to develop personalized treatment strategies for patients.
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Jun 27, 2023 | 
frontiersin.org | Alma Mater Europaea |Kyung Hee |Thanos Manos |Sorinel A. Oprisan
1. Introduction
Understanding the complicated functions of the brain of an individual has been fascinating and challenging for scientists and academics (Changeux and Dehaene, 1989). One important component of this pursuit is the development of neural models capable of capturing the activity and functionality of individual neurons as well as the networks they compose (Aihara et al., 1990; Boccaletti et al., 2006; Majhi et al., 2019).
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Jun 26, 2023 | 
frontiersin.org | Alma Mater Europaea |Philip Foster |Emad Al-Yahya |Elizabeth L. Stegemöller
Cécil J. W.
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May 31, 2023 | 
diabetesjournals.org | Marjan Slak |Alma Mater Europaea
The mechanisms accounting for the functional changes of α- and β-cells over the course of Type 1 Diabetes (T1D) development are largely unknown. Permitted by our established technology of high spatiotemporal resolution imaging of cytosolic Ca2+ ([Ca2+] ) dynamics on fresh pancreas tissue slices, we tracked the [Ca2+] dynamic changes, as the assessment of function, in islet α- and β-cells of female non-obese diabetic (NOD) mice along the development of spontaneous diabetes.
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May 19, 2023 | 
frontiersin.org | Skelin Klemen |Alma Mater Europaea |Slak Rupnik |Marcia Hiriart
IntroductionInsulin serves as an important regulator of nutrient homeostasis and a lack of its effects, either due to beta cell failure or resistance in peripheral tissues, or both, results in diabetes mellitus, which affects more than 537 million people worldwide (1). 90% of all diabetes cases are type 2 diabetes mellitus (T2DM), which is characterized by impaired insulin secretion, insulin resistance, and obesity (2).
