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Alyssa N. Coyne

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Articles

  • The expanding repertoire of ESCRT functions in cell biology and disease - Nature

    3 days ago | nature.com | James Hurley |Alyssa N. Coyne

    AbstractThe endosomal sorting complex required for transport (ESCRT) is a multicomplex machinery comprising proteins that are conserved from bacteria to humans and has diverse roles in regulating the dynamics of cellular membranes. ESCRT functions have far-reaching consequences for cell biological processes such as intracellular traffic, membrane repair, cell signalling, metabolic regulation, cell division and genome maintenance.

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