Amado J. Zurita-Saavedra

Nov 21, 2024 | nature.com | Mohamed Kamal |Amado J. Zurita-Saavedra |Kenneth J. Pienta

AbstractTherapeutic resistance in cancer significantly contributes to mortality, with many patients eventually experiencing recurrence after initial treatment responses. Recent studies have identified therapy-resistant large polyploid cancer cells in patient tissues, particularly in late-stage prostate cancer, linking them to advanced disease and relapse.