Kenneth J. Pienta

Nov 21, 2024 | nature.com | Mohamed Kamal |Amado J. Zurita-Saavedra |Kenneth J. Pienta

AbstractTherapeutic resistance in cancer significantly contributes to mortality, with many patients eventually experiencing recurrence after initial treatment responses. Recent studies have identified therapy-resistant large polyploid cancer cells in patient tissues, particularly in late-stage prostate cancer, linking them to advanced disease and relapse.

Apr 3, 2023 | nature.com | Eugene Shenderov |Tamara L. Lotan |Hao Wang |Hongkai Ji |Sarah Church |Paul Fields | +1 more

Author notesEmmanuel S. AntonarakisPresent address: University of Minnesota Masonic Cancer Center, Minneapolis, MN, USAAuthors and AffiliationsDepartment of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USAEugene Shenderov, Angelo M. De Marzo, Tamara L. Lotan, Sin Chan, Carolyn Chapman, Samuel R. Denmeade, Kenneth J. Pienta, Drew M. Pardoll & Emmanuel S.

Mar 13, 2023 | 3quarksdaily.com | Kenneth J. Pienta

by Kenneth J. PientaNo metaphor for cancer does it justice. As a medical oncologist and cancer researcher, I struggle constantly with how people perceive cancer. Until a person suffers from it or sees a loved one suffer from the devastation of this disease, cancer remains an abstract term or concept. But it is an abstract concept that kills 10 million people around the world every year. Ten million people every year.