Amin Naghdloo

Aug 23, 2024 | biorxiv.org | Michael Schmidt |Rishvanth K. Prabakar |Mohamed Kamal |Amin Naghdloo

AbstractTherapeutic resistance in cancer significantly contributes to mortality, with many patients eventually experiencing recurrence after initial treatment responses. Recent studies have identified therapy-resistant large polyploid cancer cells in patient tissues, particularly in late-stage prostate cancer, linking them to advanced disease and relapse.