Amir Seyfoori

Jul 6, 2024 | onlinelibrary.wiley.com | Mahdieh Shokrollahi Barough |Amir Seyfoori |Esfandyar Askari |Mehdi Mahdavi

1 Introduction Triple-negative breast cancer (TNBC) accounts for ≈15–25% of all breast cancer cases and is characterized by a poor prognosis and a high incidence of metastasis.

Apr 19, 2024 | biorxiv.org | Amir Seyfoori |Kaiwen Ivy Liu |Hector J Caruncho |Patrick Walter

AbstractEmploying three-dimensional (3D) in vitro models, including tumor organoids and spheroids, stands pivotal in enhancing cancer therapy. These models bridge the gap between 2D cell cultures and complex in vivo environments, effectively mimicking the intricate cellular interplay and microenvironmental factors found in solid tumors. Consequently, they offer versatile tools for comprehensive studies into cancer progression, drug responses, and tailored therapies.