Amy L. Bottomley

Oct 17, 2024 | biorxiv.org | Le Fu Zhang |Yunpeng Guan |Nural Cokcetin |Amy L. Bottomley

AbstractThe killing mechanism of many antibiotics involves the induction of DNA damage, either directly or indirectly, which triggers the SOS response. RecA, the master regulator of the SOS response, plays a crucial role in driving the evolution of resistance to fluoroquinolone antibiotics treated with a single dose of ciprofloxacin. However, the precise roles of RecA and SOS responses in the development of resistance under short-term β-lactam exposure remain unclear.

Jun 2, 2023 | kentuckyteacher.org | Amy L. Bottomley

In classrooms across the country, teachers and students are honoring notable Black Americans who demonstrated resistance and resilience by fighting injustice, breaking the color barrier and achieving greatness. Images of Harriet Tubman, Martin Luther King Jr, Jackie Robinson and Rosa Parks adorn classroom walls and the covers of featured picture books. Certainly, such individuals should hold prominent positions in U.S. history.