Yunpeng Guan

Oct 17, 2024 | biorxiv.org | Le Fu Zhang |Yunpeng Guan |Nural Cokcetin |Amy L. Bottomley

AbstractThe killing mechanism of many antibiotics involves the induction of DNA damage, either directly or indirectly, which triggers the SOS response. RecA, the master regulator of the SOS response, plays a crucial role in driving the evolution of resistance to fluoroquinolone antibiotics treated with a single dose of ciprofloxacin. However, the precise roles of RecA and SOS responses in the development of resistance under short-term β-lactam exposure remain unclear.

Sep 21, 2023 | dx.doi.org | Fang Zhao |Yunpeng Guan |Fei Su |Zhongbo Du

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