Anders Thorsen

Apr 29, 2024 | biologicalpsychiatryjournal.com | Anders Thorsen |Florence Boehmisch |Andreas Dahl |Lars T. Westlye

BackgroundEarly life adversity (ELA; childhood trauma, abuse and neglect) impacts the development of brain macrostructure, including cortical thickness and (sub)cortical volumes as measured using MRI. However, less is known about gray matter microstructure, including myelination, with preliminary animal and post-mortem human studies suggesting less myelination in adulthood after ELA. Here, we present the first longitudinal study of ELA and brain microstructure in adolescence.

Feb 15, 2023 | frontiersin.org | Martin Schevik |Andrea Poli |Liliana Pitacho |Anders Thorsen

IntroductionMental disorders are the largest contributor to the burden of disease worldwide and one of the most common causes of absenteeism (Vigo et al., 2016). These disorders are associated with great personal, social, and financial costs to employees, employers, and society (Hensing and Wahlström, 2004; Harvey et al., 2009).