
Andrea M Darby
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biorxiv.org
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1 week ago |
elifesciences.org | Sarah R Mullinax |Andrea M Darby |Anjali Gupta |Patrick Chan
eLife Assessment This valuable study investigates evolutionary aspects around a single amino acid polymorphism, known to be under long-term balancing selection, in an immune peptide of Drosophila melanogaster. Using alleles with different substitutions, the investigators demonstrate that while one allele provides better survival after systemic infections by a bacterial pathogen, the alternative allele endows its carriers with a longer lifespan under certain conditions.
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