Andrea N Loes

Mar 9, 2024 | biorxiv.org | Andrea N Loes |John Huddleston |Samuel MS Cheng |Lisa Touyon

AbstractThe high genetic diversity of influenza viruses means that traditional serological assays have too low throughput to measure serum antibody neutralization titers against all relevant strains. To overcome this challenge, we have developed a sequencing-based neutralization assay that simultaneously measures titers against many viral strains using small serum volumes via a workflow similar to traditional neutralization assays.