Andriy Marusyk

Jul 10, 2024 | nature.com | Anjali Rao |Dalia Barkley |Igor Dolgalev |Thales Papagiannakopoulos |Andriy Marusyk |Timothée Lionnet | +3 more

AbstractAdvancements in precision oncology over the past decades have led to new therapeutic interventions, but the efficacy of such treatments is generally limited by an adaptive process that fosters drug resistance1. In addition to genetic mutations2, recent research has identified a role for non-genetic plasticity in transient drug tolerance3 and the acquisition of stable resistance4,5.

Jul 4, 2024 | nature.com | Andriy Marusyk

A therapeutic strategy harnesses evolutionary dynamics to overcome tumor resistance to targeted therapies.