Angela Hickey

4 weeks ago | nanoporetech.com | Anna Maria Niewiadomska |Robert James |Christine He |Angela Hickey

Oxford Nanopore at ASM Microbe 2025In light of the recent events in Los Angeles, we’ve made the difficult decision to withdraw from ASM Microbe 2025. The decision was difficult as ASM is always a highlight for us, and we were truly looking forward to connecting with so many of you in person.​ We’re now working with our fantastic speakers— Robert James, Angela Hickey, and Jose Alexander —to bring their research to you in a virtual webinar next week.

1 month ago | biorxiv.org | Jakob Wirbel |Angela Hickey |Daniel Chang |Nora J. Enright

AbstractGut bacteriophages profoundly impact microbial ecology and human health, yet they are greatly understudied. Using deep, long-read bulk metagenomic sequencing, a technique that overcomes fundamental limitations of short-read approaches, we tracked prophage integration dynamics in 12 longitudinal stool samples from six healthy individuals, spanning a two-year timescale.

Mar 20, 2024 | biorxiv.org | Danica T. Schmidtke |Angela Hickey |Ivan Liachko |Gavin Sherlock

AbstractThe prototypic crAssphage (Carjivirus communis) is one of the most abundant, prevalent, and persistent gut bacteriophages, yet it remains uncultured and its lifestyle uncharacterized. For the last decade, crAssphage has escaped plaque-dependent culturing efforts, leading us to investigate alternative lifestyles that might explain its widespread success. Through genomic analyses and culturing, we find that crAssphage uses a phage-plasmid lifestyle to persist extrachromosomally.