Anita Chakraverty

London

Medical Eriter and Editor at Freelance

Contributor at Inside Precision Medicine

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Articles

Simple Mouth Swab Quickly Optimizes IVF Hormone Choice

2 days ago | insideprecisionmedicine.com | Anita Chakraverty

A mouth swab that reveals a woman’s genetic makeup within an hour can help decide the best form of a fertility hormone she should receive to maximize her chances of pregnancy, new research reveals. The findings, in Frontiers in Endocrinology, reveal the benefits of a genotype-guided approach to fertility treatment, and particularly the choice of gonadotropin.
Gene Regulation Does Little to Explain Protein Differences Between Sexes

3 days ago | insideprecisionmedicine.com | Anita Chakraverty

While protein levels often vary between men and women, research suggests that just a small percentage of these differences are regulated by genes. A new study indicates that other intrinsic factors, such as hormone levels, as well as extrinsic factors such as lifestyle and risk-factor profiles, play a greater role in regulating the human proteome. The findings, published in Nature Communications, could impact the development of precision medicines.
AI Tool Predicts Cancer Survival from Face Photos

1 week ago | insideprecisionmedicine.com | Anita Chakraverty

A deep-learning algorithm that predicts a person’s biological age from low-cost face photos could help determine their survival after cancer treatment, a fascinating study has revealed. The FaceAge tool offers an objective way to clinically use insights gained into a person’s biological age and physiological health from their physical appearance, and could be used for other conditions.
Many May Choose Not to Know Future Alzheimer’s Risk

1 week ago | insideprecisionmedicine.com | Anita Chakraverty

Research volunteers often do not want to find out their risk of developing Alzheimer’s disease when given the opportunity to do so from biomarker tests, a study has revealed. The findings, published in JAMA Network Open, reveal the quandary people face when offered the opportunity to discover their risk of this common form of dementia, which currently has no cure.
Eyes and Faces Reflect Tinnitus and Sound Sensitivity

2 weeks ago | insideprecisionmedicine.com | Anita Chakraverty

The eyes may be the windows to the soul, and they can also offer insight into hearing issues, a study has revealed. Researchers found that subtle dilation of the pupils, which reflects the action of the autonomic nervous system, could single out people with tinnitus and sound hypersensitivity, otherwise known as hyperacusis. The findings, in Science Translational Medicine, also showed that involuntary shifts in facial expression revealed these auditory processing disorders.
Biological Age Provides Window Into Dementia Risk

2 weeks ago | insideprecisionmedicine.com | Anita Chakraverty

Biomarkers and other measures of health that reflect a person’s biological age could offer an insight into their risks of developing dementia, a new study suggests. The findings, published in Neurology, suggest that biological aging could contribute to dementia by causing widespread changes in brain structure.
“Lab on Skin” Smart Bandage Predicts Wound Healing

3 weeks ago | insideprecisionmedicine.com | Anita Chakraverty

Researchers report that they have developed a smart bandage that can sample fluid released from a wound and detect molecular biomarkers, flagging infection days before a patient experiences symptoms. The iCares wearable device could help determine how well a wound is healing and guide treatment decisions, which usually rely on regular medical evaluation by skilled professionals.
Inherited DNA as Well as Tumor Mutations Drive Cancer

1 month ago | insideprecisionmedicine.com | Anita Chakraverty

A person’s underlying DNA as well as the specific genetic mutations in tumors determine how cancer forms and evolves and should be considered when personalizing treatment, research suggests. The findings, in the journal Cell, suggest that genes present at birth, inherited across generations in the form of germline genetic variants, are vital in shaping the protein landscape of tumors across many types of cancer.
Cholesterol-Lowering Combination Early After Heart Attacks Saves Lives

1 month ago | insideprecisionmedicine.com | Anita Chakraverty

Adding ezetimibe to statin treatment early after a heart attack could prevent many subsequent cardiac events and save lives, according to a major study that could lead to changes in clinical guidelines. The findings, published in the Journal of the American Heart Association, indicate that lowering low-density lipoprotein (LDL) cholesterol levels as quickly as possible using multiple drugs after a heart attack offers greater benefits than a more graduated method.
Oral RNA Splicing Drug Treats Cardiac Fabry Disease

1 month ago | insideprecisionmedicine.com | Anita Chakraverty

An oral medication that corrects RNA splicing errors could be used as preemptive treatment for the cardiac variant of Fabry disease (FD) and might help treat other mis-splicing genetic disorders, study findings suggest. RECTAS-2.0 is the first oral drug to act on a splicing-specific mutation that affects people with FD, a multisystemic lysosomal storage disorder that affects fat metabolism.