Inside Precision Medicine

Clinical OMICs has transformed into Inside Precision Medicine. Inside Precision Medicine stands as the sole global media outlet dedicated to covering all aspects of precision medicine. It takes a broad view while also delving into the intricate and interconnected challenges that shape this field. With its main magazine, real-time website, a range of eNewsletters, and a variety of engaging broadcast events and multimedia content, Inside Precision Medicine serves as the essential platform for robust discussions and insights that encompass technological advancements as well as complex socio-economic and public policy matters. It also aims to provide practical solutions to the gaps that exist among various stakeholders. Inside Precision Medicine is committed to innovative thinking and actively contributing to genuine progress and change, with a focus on enhancing and streamlining the precision medicine process for the benefit of patients in need. Our main focus areas include Translational Research, Molecular Diagnostics, Informatics, and Patient Care, alongside broader coverage of Disease Indications and Payer/Regulatory topics. Our top-notch content is designed to inform, educate, and enlighten a diverse audience of researchers, pathologists, clinicians, executives, and other professionals in the field.

International, Trade/B2B

English

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#545448

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#231634

Health/Health Conditions and Concerns

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Articles

Colorectal Cancer Stages Tied to Microbiome, May Improve Non-invasive Tests

2 days ago | insideprecisionmedicine.com | Jonathan Grinstein

Researchers have uncovered the potential role of gut microbes in the early detection and monitoring of colorectal cancer (CRC) in a groundbreaking international study. By analyzing stool samples from over 3,700 individuals across 18 international cohorts, the study mapped microbial changes associated with cancer stages, tumor location, and progression, refining our understanding of the microbiome as a diagnostic and prognostic tool for one of the deadliest cancers worldwide.
Drinking and Smoking Increase Early-Onset CRC Risk

3 days ago | insideprecisionmedicine.com | Malorye Allison Branca

The startling rise in colorectal cancer (CRC) among younger people has led to an intensive search for a cause of this trend. A new study led by researchers from the German Cancer Research Center (DKFZ) suggests alcohol consumption and smoking are significant risk factors for early-onset CRC (EOCRC). The authors say awareness about this link should be part of prevention efforts. The report appears in Clinical Colorectal Cancer and the lead author is Janine Wieser of the DKFZ.
Epigenetic Clock Measures Healthy Aging

3 days ago | insideprecisionmedicine.com | Helen Albert

American and French researchers have developed a blood based epigenetic ‘clock’ that can estimate how well someone is aging, reflecting both physical and mental factors. “In 2015, the World Health Organization introduced the concept of intrinsic capacity, defined as the sum of all physical and mental capacities that an individual can draw on at any point in their life.
First Personalized CRISPR Gene Editing Therapy Patient Baby KJ Discharged

4 days ago | insideprecisionmedicine.com | Jonathan Grinstein

On Tuesday, 307 days after he was first admitted to Children’s Hospital of Philadelphia (CHOP), KJ Muldoon went home after being successfully treated with the first personalized CRISPR gene editing therapy. KJ, who has a serious and rare genetic condition called severe carbamoyl phosphate synthetase 1 (CPS1), received two doses of a base editor bound to a bespoke targeting guide sequence using lipid nanoparticles (LNPs) when he was 7 and 8 months old.
First AI Platform for Breast Cancer Risk Prediction Approved By FDA

4 days ago | insideprecisionmedicine.com | Jonathan Grinstein

Throughout her career as a radiologist, Connie Lehman, MD, dedicated herself to the early detection of breast cancer. However, she came to the realization that there were limited imaging tools available for assessing the risk of breast cancer, and those that were there were heavily outdated.
Trans-Amplifying mRNA Vaccine Effective, Cheap to Develop

4 days ago | insideprecisionmedicine.com | Helen Albert

A new type of mRNA vaccine has been developed by researchers at the University of Pittsburgh and Pennsylvania State University that is more effective and cheaper to develop than vaccines currently on the market.
Dementia Risk More than Doubled in Men with Genetic Variant

5 days ago | insideprecisionmedicine.com | Helen Albert

Having two copies of a common gene variant linked to iron metabolism increases a man’s risk for dementia more than two-fold, according to Australian research. Notably, this association occurred in men but not in women, show study results published in the journal Neurology. The homeostatic iron regulator (HFE) gene regulates iron metabolism in the body and mutations in this gene are known to cause hemochromatosis—a genetic condition that leads to excess iron buildup around the body.
Pan-Cancer Proteome Atlas Catalogs 999 Primary Tumors, Available Worldwide

1 week ago | insideprecisionmedicine.com | Jonathan Grinstein

Pick a cancer that you’d like to investigate. There’s a good chance that you can now pull up that cancer’s proteome. And if you can’t, researchers have made major inroads that are paving the way for proteomic maps for more than 200 described cancers. An international collaboration of four cancer proteomics laboratories and their clinical partners released The Pan-Cancer Proteome Atlas (TPCPA), the most comprehensive tumor protein map to date.
All-Cause Mortality Risk 66% Higher in People with Both Hypertension and T2D

1 week ago | insideprecisionmedicine.com | Chris Anderson

New research from the Columbia Mailman School of Public Health shows that adults in the U.S. with both hypertension and type 2 diabetes (T2D) face a much higher risk or all-cause mortality and as a three times higher cardiovascular risk of mortality than those people with only one, or neither of these conditions.
Sperm Donor’s Cancer-Causing Mutation Prompts Calls for Better Regulation in Europe

1 week ago | insideprecisionmedicine.com | Malorye Allison Branca

The case of a sperm donor who was later found to be carrying a previously undocumented cancer-causing variant has sparked discussion about further regulating gamete donation in Europe. The donor is apparently in good health, but his biological children are at risk of Li-Fraumeni syndrome, which heightens cancer risk. Of 67 children from 46 families in eight European countries, the variant was found in 23 and cancer found in 10, to date.