Anja Torsvik

Jun 17, 2023 | nature.com | Anja Torsvik |Srdjan Djurovic |Jonelle D. Villar |Anne-Kristin Stavrum |Thomas Bjella |Niels Eiel Steen

Patients with schizophrenia and healthy controls were recruited through the Thematically Organised Psychosis (TOP) study cohort at the Norwegian Centre for Mental Disorders Research (NORMENT, Oslo, Norway; (https://www.med.uio.no/norment/english). Diagnoses were obtained by trained clinical psychologists or physicians using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) [15] with an 82% diagnostic reliability for DSM-IV diagnostic categories [16].

May 5, 2023 | nature.com | Timothy Hughes |Nils Eiel Steen |Ingrid Melle |Srdjan Djurovic |Ole A. Andreassen |Anja Torsvik | +1 more

AbstractSchizophrenia (SCZ) and bipolar disorder (BD) share clinical characteristics, genetic susceptibility, and immune alterations. We aimed to identify differential transcriptional patterns in peripheral blood cells of patients with SCZ or BD versus healthy controls (HC). We analyzed microarray-based global gene expression data in whole blood from a cohort of SCZ (N = 329), BD (N = 203) and HC (N = 189).