Anmol Goyal

Jul 1, 2024 | jitc.bmj.com | Eric Lau |Mark Hamilton |Anmol Goyal |Sushma Bharadwaj

DiscussionLD chemotherapy plays a critical role in the expansion and persistence of infused CAR T-cells. While CAR T-cell therapy has revolutionized the treatment of non-Hodgkin’s lymphoma, the incidence of CAR T-cell therapy-related toxicity is high and contributes to morbidity and mortality. In addition to drug shortage situations, there is a need to study alternative LD regimens to improve safety while preserving efficacy.