Mark Hamilton

2 months ago | cgtlive.com | Mark Hamilton |Noah Stansfield

The FDA began requiring black box warnings for commercially available autologous chimeric antigen receptor T-cell (CAR-T) therapy products in early 2024, with the move made in relation to the potential risk for the development of secondary T-cell malignancies after treatment.1 Notably, a study being conducted at Stanford University seeking to better understand this risk was recently presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition, held December 7-10,...

Sep 23, 2024 | lexology.com | Laura Jackson |Mark Hamilton

It is World Mental Health Day on 10 October 2024. This year’s theme is “It’s Time to Prioritise Mental Health in the Workplace”. The theme highlights the importance of addressing mental health and wellbeing at work, recognising that doing so benefits not just employees, but organisations and communities as a whole. Mental health issues, such as stress, anxiety and burn-out, not only significantly impact employees' general wellbeing, but in turn their performance and morale at work.

Jul 1, 2024 | jitc.bmj.com | Eric Lau |Mark Hamilton |Anmol Goyal |Sushma Bharadwaj

DiscussionLD chemotherapy plays a critical role in the expansion and persistence of infused CAR T-cells. While CAR T-cell therapy has revolutionized the treatment of non-Hodgkin’s lymphoma, the incidence of CAR T-cell therapy-related toxicity is high and contributes to morbidity and mortality. In addition to drug shortage situations, there is a need to study alternative LD regimens to improve safety while preserving efficacy.

Feb 13, 2024 | lexology.com | Mark Hamilton |Helena Rozman

The Employment Appeal Tribunal (EAT) recently provided clarifications on key aspects of constructive dismissal – in particular, acceptance of the employer's breach (affirmation) and delay. The EAT ruled in Leaney v. Loughborough University that, when considering affirmation and constructive dismissal, all relevant features of the case should be carefully considered and that too much focus should not be put on the length of any delay.

Sep 8, 2023 | thejns.org | Mark Hamilton

Correspondence Mark G. Hamilton: [email protected]. INCLUDE WHEN CITING Published online September 8, 2023; DOI: 10.3171/2023.7.JNS231284.