Ann Ly

Nov 12, 2024 | cell.com | Yiqian Gu |Ann Ly |Sara Rodriguez |Sara Rodríguez |Hanwei Zhang |Jiyoon Kim | +8 more

Keywords small cell cancers small cell bladder cancer neuroendocrine prostate cancer PD-1 blockade immunochemotherapy clinical trial single-cell sequencing T cell receptor sequencing Introduction Small cell carcinomas (SCCs) are aggressive malignancies found in multiple tissue types including the lung, bladder, prostate, ovaries, and breast.1 They share common histologic features such as small, round-to-oval cells with high nuclear-to-cytoplasm ratios, inconspicuous nucleoli, and incomplete...