Anton Sculean

Mar 28, 2024 | onlinelibrary.wiley.com | Richard Miron |Nathan E. Estrin |Anton Sculean |Yufeng Zhang

1 INTRODUCTION Exosomes are the smallest extracellular vesicles; they range in size from 30 to 150 nm and are found in the majority of bodily fluids.1 They can transport functional miRNAs, coupled with the inherent biological functions of exosomes, which makes them a novel delivery platform for gene therapy.2 Exosomes have many advantages as new drug delivery tools—specifically, they have the characteristics of low immunogenicity and high transport efficiency, they can regulate inflammation,...

Nov 30, 2023 | onlinelibrary.wiley.com | Richard Miron |Reinhard P. Gruber |Nima Farshidfar |Anton Sculean

1 INTRODUCTION The use of platelet concentrates has gained tremendous popularity in the fields of regenerative medicine and dentistry owing to their ability to speed healing through improving neovascularization.1 Platelet-rich plasma (PRP) is derived from peripheral blood following centrifugation with anticoagulants. Over the years, a second-generation platelet concentrate was developed with the main aim of anticoagulant removal.