
Articles
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1 week ago |
onclive.com | Ashling Wahner
Ibrutinib (Imbruvica) in combination with lenalidomide (Revlimid) and rituximab (Rituxan; IR2) produced durable responses in patients with relapsed/refractory mantle cell lymphoma (MCL), including initial activity in patients with TP53 mutations, according to long-term follow-up findings from the phase 2 Philemon trial (NCT02460276) published in Hemasphere.
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1 week ago |
onclive.com | Ashling Wahner
Prophylactic enhanced dermatologic management significantly reduced the incidence of grade 2 or higher dermatologic adverse effects (AEs) vs standard dermatologic management within the first 12 weeks of first-line amivantamab-vmjw (Rybrevant)/lazertinib (Lacluze) treatment in patients with EGFR-mutated advanced non–small cell lung cancer (NSCLC), meeting the primary end point of the first preplanned interim analysis of the phase 2 COCOON trial (NCT06120140).1 Findings, which were presented at...
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1 week ago |
onclive.com | Megan Hollasch |Ashling Wahner
Each research step that reveals patterns of activity with targeted therapies in endometrial cancer—such as metformin and temsirolimus (Torisel)—brings the field closer to developing increasingly effective and better-tolerated regimens that improve upon historical treatment results and quality of life (QOL) outcomes, according to Pamela T. Soliman, MD, MPH.
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1 week ago |
cancernetwork.com | Ashling Wahner
According to a study from New York University Langone Health’s Perlmutter Cancer Center, implementing comprehensive patient and health care provider education on bispecific T-cell engager (BiTE) therapy toxicities, including cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), and improving multidisciplinary strategies of monitoring patients, has improved the safe administration of these agents in both inpatient and outpatient settings.1 In a...
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1 week ago |
onclive.com | Ashling Wahner
A single infusion of ciltacabtagene autoleucel (cilta-cel; Carvykti) delayed worsening of disease-related symptoms and functional effects in patients with lenalidomide (Revlimid)–refractory multiple myeloma, who also experienced improved quality of life (QOL) over time compared with those who received standard of care (SOC), according to long-term findings from the phase 3 CARTITUDE-4 trial (NCT04181827).1 The findings, which were presented at the 50th Annual Oncology Nursing Society...
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