Ashutosh K. Rai

Jun 24, 2024 | journals.plos.org | Ashutosh K. Rai |Katsuhiro Sawasato |Haley Bennett |Anastasiia A. Kozlova

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Rai AK, Sawasato K, Bennett HC, Kozlova A, Sparagna GC, Bogdanov M, et al. (2024) Genetic evidence for functional diversification of gram-negative intermembrane phospholipid transporters. PLoS Genet 20(6): e1011335.

May 13, 2024 | biorxiv.org | Ashutosh K. Rai |Katsuhiro Sawasato |Haley Bennett |Anastasiia A. Kozlova

AbstractThe outer membrane of Gram-negative bacteria is a barrier to chemical and physical stress. Phospholipid transport between the inner and outer membranes has been an area of intense investigation and, in E. coli K-12, it has recently been shown to be mediated by YhdP, TamB, and YdbH, which are suggested to provide hydrophobic channels for phospholipid diffusion, with YhdP and TamB playing the major roles. However, YhdP and TamB have different phenotypes suggesting distinct functions.

Mar 19, 2024 | biorxiv.org | Ashutosh K. Rai |Katsuhiro Sawasato |Haley Bennett |Anastasiia A. Kozlova

AbstractThe outer membrane of Gram-negative bacteria is a barrier to chemical and physical stress. Phospholipid transport between the inner and outer membranes has been an area of intense investigation and, in E. coli K-12, it has recently been shown to be mediated by YhdP, TamB, and YdbH, which are suggested to provide hydrophobic channels for phospholipid diffusion, with YhdP and TamB playing the major roles. However, YhdP and TamB have different phenotypes suggesting distinct functions.