Ashutosh K Rai

Aug 15, 2024 | digitalcommons.library.tmc.edu | Katsuhiro Sawasato |Haley Bennett |Anastasiia A. Kozlova |Ashutosh K Rai

AbstractThe outer membrane of gram-negative bacteria is a barrier to chemical and physical stress. Phospholipid transport between the inner and outer membranes has been an area of intense investigation and, in E. coli K-12, it has recently been shown to be mediated by YhdP, TamB, and YdbH, which are suggested to provide hydrophobic channels for phospholipid diffusion, with YhdP and TamB playing the major roles. However, YhdP and TamB have different phenotypes suggesting distinct functions.