Aurore Lyon

Dec 28, 2023 | journals.physiology.org | Natalia A. Trayanova |Aurore Lyon |Julie K. Shade |Jordi Heijman

CLINICAL HIGHLIGHTSComputational modeling of the heart has become an important research tool in cardiac electrophysiology and arrhythmias, as it provides a link between effects at the subcellular level, including genetic mutations and protein function, and emergent electrophysiological phenomena at the organ level. Electrophysiological models of the heart are currently being employed in real-world applications in mechanistic research, safety pharmacology, and personalized therapy.