Aylin Gulmez

Nov 1, 2023 | biorxiv.org | Lauren Reynolds |Sophie L. Fayad |Aylin Gulmez |Daiana Rigoni

AbstractNicotine use during adolescence is largely associated with negative long-term outcomes, including addiction to nicotine in adulthood. How nicotine acts on developing neurocircuitry in adolescence remains largely unknown, but may hold the key for informing more effective intervention efforts. We found transient nicotine exposure in early adolescence was sufficient for adult mice to show a marked vulnerability to nicotine.