Becca Bonham-Carter

Oct 11, 2023 | biorxiv.org | Becca Bonham-Carter |Geoffrey Schiebinger

AbstractWe identify a fundamental statistical phenomenon in single-cell time courses with clone-based lineage tracing. Through simple probabilistic arguments, we show how the relative growth rates of cells influence the probability that they will be sampled in clones observed across multiple time points.

Oct 10, 2023 | biorxiv.org | Yale Michaels |Matthew C. Major |Becca Bonham-Carter |Jingqi Zhang

AbstractT cells develop from multi-potent hematopoietic progenitors in the thymus and provide adaptive protection against pathogens and cancer. However, the emergence of human T cell-competent blood progenitors, and their subsequent specification to the T lineage, has been challenging to capture in real time.

Jul 23, 2023 | biorxiv.org | Geoffrey Schiebinger |Becca Bonham-Carter

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