Ben Raffield

Jan 1, 2025 | nature.com | Leo Speidel |Marina Silva |Thomas Booth |Ben Raffield |Kyriaki Anastasiadou |Christopher Barrington

AbstractMany known and unknown historical events have remained below detection thresholds of genetic studies because subtle ancestry changes are challenging to reconstruct. Methods based on shared haplotypes1,2 and rare variants3,4 improve power but are not explicitly temporal and have not been possible to adopt in unbiased ancestry models.

Mar 19, 2024 | biorxiv.org | Leo Speidel |Marina Silva |Thomas J. Booth |Ben Raffield

AbstractAncient DNA has unlocked new genetic histories and shed light on archaeological and historical questions, but many known and unknown historical events have remained below detection thresholds because subtle ancestry changes are challenging to reconstruct. Methods based on sharing of haplotypes and rare variants can improve power, but are not explicitly temporal and have not been adopted in unbiased ancestry models.