Bing H. Wang

Jan 8, 2025 | nature.com | Daniela Gjorgjevikj |Naveen Kumar |Bing H. Wang |Tarek Hilal |Bernhard Loll |Irina Artsimovitch

AbstractMany bacteriophages modulate host transcription to favor expression of their own genomes. Phage satellite P4 polarity suppression protein, Psu, a building block of the viral capsid, inhibits hexameric transcription termination factor, ρ, by presently unknown mechanisms. Our cryogenic electron microscopy structures of ρ-Psu complexes show that Psu dimers clamp two inactive, open ρ rings and promote their expansion to higher-oligomeric states.

Sep 30, 2024 | nph.onlinelibrary.wiley.com | Qianqian Li |Bing H. Wang |Hong Yu

Plants suffer from various environmental stresses during their growth and development. Low temperature, a major abiotic stress, adversely affects crop growth and productivity. Therefore, improving low-temperature tolerance is one of the main goals of crop breeding. Strigolactones (SLs) are a group of carotenoid-derived phytohormones that play a vital role in plant growth, development, and environmental adaptation.

Aug 30, 2024 | nature.com | Bing H. Wang |Irina Artsimovitch

AbstractAfter an RNA polymerase reaches a terminator, instead of dissociating from the template, it may diffuse along the DNA and recommence RNA synthesis from the previous or a different promoter. Magnetic tweezers were used to monitor such secondary transcription and determine the effects of low forces assisting or opposing translocation, protein roadblocks, and transcription factors. Remarkably, up to 50% of Escherichia coli (E. coli) RNA polymerases diffused along the DNA after termination.

May 30, 2024 | 4spepublications.onlinelibrary.wiley.com | Yong Liao |Bing H. Wang |Hongyue Wang |Songhe Meng

CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , , et al. Advances in mechanics of hierarchical composite materials. Compos Sci Technol. 2021; 214:108970. 2, , , et al. Recent advances of interphases in carbon fiber-reinforced polymer composites: a review. Compos Part B Eng. 2022; 233:109639. 3, , , .

May 8, 2024 | bmjopen.bmj.com | Helen Marshall |James Ward |Bing H. Wang |Prabha H Andraweera

Methods and analysis Standard Protocol Items: Recommendations for Intervention Trials checklist was used when developing this protocol.23 The target population includes (1) all 15–19 years old in the NT during the period of six pre-vaccination years (March 2015 to February 2021) and two post-vaccination years (March 2024 to February 2026); (2) all 15–19 years old in SA during the period of six pre-vaccination years (February 2011 to January 2017) and four post-vaccination years (February 2022...