Bing H. Wang

Jan 8, 2025 | nature.com | Daniela Gjorgjevikj |Naveen Kumar |Bing H. Wang |Tarek Hilal |Bernhard Loll |Irina Artsimovitch

AbstractMany bacteriophages modulate host transcription to favor expression of their own genomes. Phage satellite P4 polarity suppression protein, Psu, a building block of the viral capsid, inhibits hexameric transcription termination factor, ρ, by presently unknown mechanisms. Our cryogenic electron microscopy structures of ρ-Psu complexes show that Psu dimers clamp two inactive, open ρ rings and promote their expansion to higher-oligomeric states.

Nov 6, 2024 | nature.com | Bing H. Wang

Traditional English corpora mainly collect information from a single modality, but lack information from multimodal information, resulting in low quality of corpus information and certain problems with recognition accuracy. To solve the above problems, this paper proposes to introduce depth information into multimodal corpora, and studies the construction method of English multimodal corpora that integrates electronic images and depth information, as well as the speech recognition method of the corpus. The multimodal fusion strategy adopted integrates speech signals and image information, including key visual information such as the speaker’s lip movements and facial expressions, and uses deep learning technology to mine acoustic and visual features. The acoustic model in the Kaldi toolkit is used for experimental research.Through experimental research, the following conclusions were drawn: Under 15-dimensional lip features, the accuracy of corpus A under monophone model was 2.4% higher than that of corpus B under monophone model when the SNR (signal-to-noise ratio) was 10dB, and the accuracy of corpus A under the triphone model at the signal-to-noise ratio of 10dB was 1.7% higher than that of corpus B under the triphone model at the signal-to-noise ratio of 10dB. Under the 32-dimensional lip features, the speech recognition effect of corpus A under the monophone model at the SNR of 10dB was 1.4% higher than that of corpus B under the monophone model at the SNR of 10dB, and the accuracy of corpus A under the triphone model at the SNR of 10dB was 2.6% higher than that of corpus B under the triphone model at the SNR of 10dB. The English multimodal corpus with image and depth information has a high accuracy, and the depth information helps to improve the accuracy of the corpus.

Sep 30, 2024 | nph.onlinelibrary.wiley.com | Qianqian Li |Bing H. Wang |Hong Yu

Plants suffer from various environmental stresses during their growth and development. Low temperature, a major abiotic stress, adversely affects crop growth and productivity. Therefore, improving low-temperature tolerance is one of the main goals of crop breeding. Strigolactones (SLs) are a group of carotenoid-derived phytohormones that play a vital role in plant growth, development, and environmental adaptation.

Aug 30, 2024 | nature.com | Bing H. Wang |Irina Artsimovitch

AbstractAfter an RNA polymerase reaches a terminator, instead of dissociating from the template, it may diffuse along the DNA and recommence RNA synthesis from the previous or a different promoter. Magnetic tweezers were used to monitor such secondary transcription and determine the effects of low forces assisting or opposing translocation, protein roadblocks, and transcription factors. Remarkably, up to 50% of Escherichia coli (E. coli) RNA polymerases diffused along the DNA after termination.

May 30, 2024 | 4spepublications.onlinelibrary.wiley.com | Yong Liao |Bing H. Wang |Hongyue Wang |Songhe Meng

CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , , et al. Advances in mechanics of hierarchical composite materials. Compos Sci Technol. 2021; 214:108970. 2, , , et al. Recent advances of interphases in carbon fiber-reinforced polymer composites: a review. Compos Part B Eng. 2022; 233:109639. 3, , , .