Bingjie Wang

Nov 15, 2024 | biorxiv.org | Bingjie Wang |Haiyan Zhao

AbstractTick-borne encephalitis virus (TBEV) is primarily transmitted to humans through tick bites, leading to symptoms of encephalitis with a fatality rate ranging from 1% to 30%, depending on the virus subtype. Currently, only inactivated virus vaccines are available for human use, though break-through infections can still occur. Therefore, developing new vaccines against TBEV is crucial. In this study, we designed and characterized a novel nanoparticle-based TBEV envelope (E) dimer vaccine.

Oct 28, 2024 | biorxiv.org | Bingjie Wang

AbstractTick-borne encephalitis virus (TBEV) is a serious pathogen that poses a significant threat to humans, causing encephalitis that can result in lifelong sequelae. In this study, we focused on the complete proteomes of the five current TBEV subtypes to identify dominant epitopes. Immunoinformatics tools were employed to screen for LBL, HTL, and CTL epitopes. These epitopes were then linked using various linkers and combined with adjuvants and histidine tag.

Sep 18, 2024 | onlinelibrary.wiley.com | Bingjie Wang

1. Introduction In a global context, the trend of urbanization is becoming increasingly evident. It is estimated that by the year 2050, the global urban population will increase by 2.5 billion, with China contributing an additional 255 million (source: United Nations Department of Economic and Social Affairs, Population Division, “World Urbanization Prospects: The 2018 Revision”).

Jul 9, 2024 | mdpi.com | Bingjie Wang |Yingzi Zhang

1. IntroductionDesertification, a concerning environmental phenomenon, represents the gradual transformation of fertile land into arid desert landscapes due to various factors such as climate change, unsustainable land management practices, and human activities.

Jun 26, 2024 | iopscience.iop.org | Bingjie Wang |Joel Leja |Anna de Graaff |Max-Planck-Institut für Astronomie

In the cores of the most massive galaxies in the local Universe, stars have inferred stellar age of ∼13 Gyr and high α-element abundance, suggesting that their stellar components are formed at z ≳ 5 in a spectacular and short burst of star formation (e.g., Thomas et al. 2005).