Bingxiang Xu

Sep 29, 2024 | nature.com | Bingxiang Xu |Feifei Li

AbstractFormaldehyde (FA) is a chemical that facilitates crosslinking between DNA and proteins. It is widely used in various biochemical assays, such as chromosome conformation capture (3C) and Chromatin Immunoprecipitation (ChIP). While the concentration and temperature of FA treatment are recognized as crucial factors in crosslinking, their quantitative effects have largely remained unexplored.

Mar 4, 2024 | medrxiv.org | Cheng Liu |Xinyu Hou |Bingxiang Xu |Tiemin Liu

The authors have declared no competing interest. This study did not receive any fundingI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.