Feifei Li Journalist Profile

Articles

Crosslinking intensity modulates the reliability and sensitivity of chromatin conformation detection at different structural levels - Communications Biology

Sep 29, 2024 | nature.com | Bingxiang Xu |Feifei Li

AbstractFormaldehyde (FA) is a chemical that facilitates crosslinking between DNA and proteins. It is widely used in various biochemical assays, such as chromosome conformation capture (3C) and Chromatin Immunoprecipitation (ChIP). While the concentration and temperature of FA treatment are recognized as crucial factors in crosslinking, their quantitative effects have largely remained unexplored.
Synthesis and Antibacterial Activity of 8-Ketoberberine Derivatives

Aug 4, 2024 | academic.oup.com | Shanghai Academy |Feifei Li

Natural berberine (BBR) exhibits good antimicrobial efficacy, however, its limited bioavailability greatly hinder its clinical application. In this study, 18 novel lipophilic C-8-substituted BBR prodrugs were synthesized and tested for in vitro antimicrobial activity against four common clinical pathogens, and the inhibitory mechanism was further investigated with respect to the ability of bacterial membrane formation, cell permeability, hydrophobicity, and self-cohesion.
Urban Green-Blue Space Utilization and Public Perceptions Amid the COVID-19 Pandemic: Insights from Northwest China

Apr 18, 2024 | mdpi.com | Yuliang Wang |Feifei Li |Dan Liu |Zilong Zhang

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
Research Progress on Benzimidazole Fungicides: A Review

Mar 8, 2024 | mdpi.com | Feifei Li |Song Bai |Miaohe Zhang |Shouying Tang |Miao Li

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.