-
Jan 14, 2025 | 
jamanetwork.com | Muhammad Ali |Biomedical Informatics |Cindy X. Cai |Martin Makary
Geographic Distribution of US Ophthalmic Surgical Subspecialists Key PointsQuestion What is the geographic distribution of ophthalmic surgical subspecialist surgeons in the US and what surgeon demographics are associated with rural practice? Findings This cross-sectional study between 2012 and 2022 identified higher proportions of rural patients compared with rural surgeons.
-
Jan 6, 2025 | 
bmcbioinformatics.biomedcentral.com | Biomedical Informatics
In this work we consider perturbation experiments on a RAFi-resistant melanoma cell line SkMel-133 originally collected in [4]. The data structure is depicted in Fig. 1a. The cell line was treated with 89 drug perturbations (rows). Perturbations are defined by the concentrations of 12 drugs (12 columns of blue matrix). Drugs were applied as a single agent and in combinations of two drugs.
-
Nov 9, 2024 | 
academic.oup.com | Rockville Pike |Biomedical Informatics |W John
Over 55% of author names in PubMed are ambiguous: the same name is shared by different individual researchers. This poses significant challenges on precise literature retrieval for author name queries, a common behavior in biomedical literature search. In response, we present a comprehensive dataset of disambiguated authors. Specifically, we complement the automatic PubMed Computed Authors algorithm with the latest ORCID data for improved accuracy.
-
Nov 4, 2024 | 
academic.oup.com | Amherst College |Biomedical Informatics
Obesity is a risk factor for increased lung damage and disease severity during influenza virus infection. White adipose tissue (WAT) inflammation is a key driver of disease pathogenesis in obesity. Whether and how obesity modifies lung and WAT immune cell character and function in obesity to amplify influenza disease severity remains unknown. We show that obesity establishes a proinflammatory transcriptome in lung immune cells that is further augmented upon influenza virus infection.
-
Oct 23, 2024 | 01245-2&sz=64)
cell.com | Biomedical Informatics |Lesley Probert
Keywords demyelination remyelination microglia multiple sclerosis TNF IL-1 DAM neuroinflammation neuromyelitis optica oligodendrocyte differentiation Research topic(s) CP: Neuroscience CP: Immunology Introduction The failure to maintain or repair myelin in the adult central nervous system (CNS) is a characteristic of demyelinating diseases such as multiple sclerosis (MS) and suggests that spontaneous repair mechanisms such as remyelination are inadequate.1 Microglia are CNS-resident immune...
-
Oct 17, 2024 | 
link.springer.com | Biomedical Informatics |Stephanie A. S
AbstractIntegrating advanced machine-learning (ML) algorithms into clinical practice is challenging and requires interdisciplinary collaboration to develop transparent, interpretable, and ethically sound clinical decision support (CDS) tools. We aimed to design a ML-driven CDS tool to predict opioid overdose risk and gather feedback for its integration into the University of Florida Health (UFHealth) electronic health record (EHR) system.
-
Oct 9, 2024 | 
jamanetwork.com | Jeremy Balch |Biomedical Informatics |Matthew Ruppert |Timothy Buchanan
Risk-Specific Training Cohorts to Address Class Imbalance in Surgical Risk Prediction
Key PointsQuestion
Can performance of machine learning–enabled surgical risk prediction models be improved using a priori knowledge of Common Procedure Terminology–associated risk class?
-
Sep 29, 2024 | 
molecularautism.biomedcentral.com | Biomedical Informatics |Neuroscience Paris Seine
Funded by the Patient Centered Outcome Research Institute (PCORI), the PMS Data Network (PMS_DN) project aims to advance knowledge about PMS and related conditions by integrating patient-reported outcomes, curated genetic test results, and knowledge extracted from clinical records in the centralized i2b2/tranSMART platform to facilitate patient-centered research [29]. Clinical records were not used in this study.
-
Sep 27, 2024 | 
trialsjournal.biomedcentral.com | Gold Coast |Biomedical Informatics
Allied Health Research, Gold Coast Health, Southport, QLD, 4215, AustraliaLaetitia HattinghSchool of Pharmacy, The University of Queensland, Brisbane, QLD, 4102, AustraliaLaetitia Hattingh, Holly Foot & Leslie E. OldfeldSchool of Pharmacy and Medical Sciences, Grifth University, Gold Coast, QLD, 4222, AustraliaLaetitia HattinghBiomedical Informatics and Digital Health, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, 2050, AustraliaMelissa T.
-
Sep 26, 2024 | 
trialsjournal.biomedcentral.com | Gold Coast |Biomedical Informatics
The proposed study aims to improve medicine handover and digital communication between hospitals, GPs, and community pharmacists when patients are discharged from hospital to primary care. It also aims to increase the uptake of post-discharge medication management reviews by community and credentialed pharmacists. We hypothesise that the co-designed multifaceted intervention will reduce 30-day medication-related hospital readmissions.
