Lesley Probert

Oct 23, 2024 | cell.com | Biomedical Informatics |Lesley Probert

Keywords demyelination remyelination microglia multiple sclerosis TNF IL-1 DAM neuroinflammation neuromyelitis optica oligodendrocyte differentiation Research topic(s) CP: Neuroscience CP: Immunology Introduction The failure to maintain or repair myelin in the adult central nervous system (CNS) is a characteristic of demyelinating diseases such as multiple sclerosis (MS) and suggests that spontaneous repair mechanisms such as remyelination are inadequate.1 Microglia are CNS-resident immune...