Bo Tang

Dec 18, 2024 | pubs.rsc.org | Bo Tang

Cu-MOF-based targeted nanomedicine utilizing biorthogonally catalyzed chemotherapy and chemodynamic therapy with spatiotemporal orchestration to treat hepatocellular carcinoma A nanomedicine was developed using a Cu-based metal-organic framework (MOF) to co-deliver Cu(I) and prodrugs for targeted biorthogonally catalyzed chemotherapy and chemodynamic therapy of hepatocellular carcinoma.

Dec 18, 2024 | pubs.rsc.org | Bo Tang

H2O2 accumulation promoting internalization of ox-LDL in early atherosclerosis revealed via a synergistic dual-functional NIR fluorescence probe† The equilibrium of lipid metabolism is critical to sustaining human health. Metabolic disorders often result in a variety of cardiovascular illnesses, especially atherosclerosis. Atherosclerosis is characterized by complicated complications and high mortality.

Dec 11, 2024 | pubs.rsc.org | Bo Tang

Intrinsically Photosensitive Polyimide Photoresist and Its Double Crosslinking Mechanism A new negative-working photoinitiator-free polyimide was developed for photolithographic process. The polyimide introduced photosensitive benzophenone unit into the backbone and cross-linking group (methacrylate) into the side chains. A novel pre-functionalized diamine monomer was designed to avoid using corrosive sulfonyl chloride in the polyimide side-chain introduction step.

Nov 22, 2024 | pubs.rsc.org | Bo Tang

May 23, 2024 | academic.oup.com | Bo Tang |Chenchen Qin

Lymphocyte trafficking via chemokine receptors such as CCR5 and CXCR3 plays a critical role in the pathogenesis of aGVHD. Our previous studies showed that addition of CCR5 or CXCR3 antagonist could only slightly alleviate the development of aGVHD. Given the specificity of T lymphocytes bearing CXCR3 and CCR5, we investigated whether combined CCR5 and CXCR3 blockade could further attenuate murine aGVHD.