Botao Zhao

Jan 18, 2024 | onlinelibrary.wiley.com | Ying Liu |Yin Chao Wu |Yang Ji |Botao Zhao

Background Quantitative in-situ pH mapping of gliomas is important for therapeutic interventions, given its significant association with tumor progression, invasion, and metastasis. Although chemical exchange saturation transfer (CEST) offers a noninvasive way for pH imaging based on the pH-dependent exchange rate (ksw), the reliable quantification of ksw in glioma remains constrained due to technical challenges.

Jan 18, 2024 | pericles.pericles-prod.literatumonline.com | Ying Liu |Yin Chao Wu |Yang Ji |Botao Zhao

Background Quantitative in-situ pH mapping of gliomas is important for therapeutic interventions, given its significant association with tumor progression, invasion, and metastasis. Although chemical exchange saturation transfer (CEST) offers a noninvasive way for pH imaging based on the pH-dependent exchange rate (ksw), the reliable quantification of ksw in glioma remains constrained due to technical challenges.